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Normal Myelination of the Pediatric Brain Imaged with Fluid-Attenuated Inversion-Recovery (FLAIR)MR Imaging

James W. MurakamiGo,a, Ed Weinbergera and Dennis W. W. Shawa

a From the Department of Radiology, CH-69, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98105.



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  		FIG 1. A–I, Matching T1-weighted, T2-weighted, and FLAIR images from three patients ages 5 weeks (A–C), 8 months (D–F), and 3 years (G–I). Note the triphasic signal progression in the deep frontal white matter on the FLAIR images, and that the FLAIR image of the 8 month old (F) looks deceivingly like a T1-weighted image (D, G) except for the internal capsule, which is hypointense rather than hyperintense relative to adjacent gray matter.

A, T1-weighted image, 600/11 (TR/TE); B, T2-weighted image, 4000/119 (TR/TEeff), split echo train with ETL = 8; C, FLAIR image, 10,002/149 (TR/TEeff) TI = 2200, ETL = 8; D, T1-weighted image, 2000/11 (TR/TE), TI = 800; E, T2-weighted image, 3000/119 (TR/TEeff), split echo train with ETL = 8; F, FLAIR image, 10,002/149 (TR/TEeff), TI = 2200, ETL = 8; G, T1-weighted image, 500/11 (TR/TE); H, T2-weighted image, 3000/80 (TR/TEeff), split echo train with ETL = 8; I, FLAIR image, 10,002/149 (TR/TEeff), TI = 2200, ETL = 8.





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X