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MR Findings in AIDS-Associated MyelopathyGo

June Chonga, Alessandro Di Roccoa, Michele Tagliatia, Fabio Danisia, David M. Simpsona and Scott W. AtlasGo,a

a From the Departments of Radiology (J.C., S.W.A.) and Neurology (A.D.R., M.T., F.D., D.M.S.), Mount Sinai School of Medicine, New York.



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  		FIG 1. A–C, T1-weighted sagittal (A), T2-weighted sagittal (B), and T2-weighted axial (C) MR images through the thoracic spine of an AIDS patient with mild myelopathy show cord atrophy and intramedullary cord signal abnormality



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  		FIG 2. A–C, Sagittal T1-weighted (A), sagittal T2-weighted (B), and axial T2-weighted (C) MR images of the cervical spine in a patient with severe myelopathy show cervical cord atrophy and extensive abnormal intrinsic cord signal intensity



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  		FIG 3. A and B, Noncontrast sagittal T1-weighted (A) and T2-weighted (B) images show a normal-sized cervicothoracic cord with intramedullary thoracic cord signal abnormality and no associated cord enlargement. There was no evidence of abnormal enhancement in the postcontrast study (not shown)



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  		FIG 4. A, Luxol fast blue stain of the spinal cord in a patient with AIDS-associated myelopathy (not from our series) shows pathologic changes predominantly involving the posterior and lateral columns (arrows).

B, A magnified view of the same specimen as in A shows vacuolization (small arrows) and lipid-laden macrophages (large arrows) scattered throughout the involved cord.

(Reprinted with permission from Mandell GL. Atlas of Infectious Diseases, I: AIDS. 2nd ed. Philadelphia: Current Medicine, Inc; 1997.)





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X