Traumatic Brain Injury: Diffusion-Weighted MR Imaging Findings
Amon Y. Liua,
Joseph A. Maldjian
,a,
Linda J. Bagleya,
Grant P. Sinsona and
Robert I. Grossmana
a From the Departments of Radiology (A.Y.L., J.A.M., L.J.B., R.I.G.) and Neurosurgery (G.P.S.), Hospital of the University of Pennsylvania.

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FIG 1. Case 2: 52 year-old man with intracranial injuries sustained in a motor vehicle accident. Brain MR imaging was performed 18 days after the accident.
A and B, Axial fast spin-echo T2-weighted (4000/98/1) (A) and FLAIR (11000/125/1) (B) images both show evidence of diffuse axonal injury, as evidenced by hyperintense signal in the splenium.
C and D, Isotropic diffusion-weighted (10000/125/1) (C) and diffusion trace (D) images show hyperintense signal and decreased ADC values, respectively, consistent with cellular edema. Of particular interest in this case is that ADC values were decreased well into the subacute period after the injury.
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FIG 2. Case 8: 40 year-old man examined with brain MR imaging 7 days after injury.
A and B, Axial fast spin-echo (4000/98/1) (A) and FLAIR (11000/125/1) (B) images at the level of the splenium confirm diffuse axonal injury, with hyperintense signal seen on both pulse sequences. Also note the small bilateral frontal subdural hematomas and a small contusion in the left anterior temporal lobe.
C and D, Isotropic diffusion-weighted (10000/125/1) (C) and diffusion trace (D) images show hyperintense signal and decreased ADC values, respectively.
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