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AJNR - American Journal of Neuroradiology

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Malignant Ectopic Thymoma in the Neck: A Case Report

Jung Im Jung^,a, Hak Hee Kim^a, Seog Hee Park^a and Youn Soo Lee^a

^a From the Departments of Radiology (J.I.J., H.H.K., S.H.P.) and Pathology (Y.S.L.), St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

View larger version (190K): [in a new window]   FIG 1. Contrast-enhanced CT scan of the neck shows a well-defined, round mass in the left jugulodigastric area (arrows). The mass enhances peripherally with central hypoattenuation. It compresses the internal carotid artery medially. Two lymph nodes of less than 1 cm in diameter were also noted in the posterior neck. No evidence of abnormality was seen in left tongue base.FIG 2. The tumor is composed of a mixture, in varying proportions, of epithelial cells and lymphocytes. Hassall's corpuscle, which is typically demonstrated in thymoma, is noted (arrowheads) (magnification, x40).FIG 3. Follow-up contrast-enhanced CT scan of the neck, obtained 1 year after surgery, shows a 2 x 3-cm, ill-defined mass in the left tongue base (arrows). This mass is isodense to the tongue muscle. Several conglomerate nodules are noted in left posterior neck (arrowheads), which show central hypoattenuation with peripheral rim enhancement

View larger version (142K): [in a new window]   FIG 4. A, Low magnification view of the tongue mass (x40) shows ill-defined infiltrative solid tumor. Tongue tissue, including muscle and salivary gland, is noted inferiorly. B, High-magnification view of the tongue mass (x200) shows epithelial cells and Hassall's corpuscles. The tumor is more aggressive than primary neck mass and shows some mitosis (arrowheads).