Advanced

AJNR - American Journal of Neuroradiology

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Burtscher, I. M. Articles by Holtås, S. Search for Related Content PubMed PubMed Citation Articles by Burtscher, I. M. Articles by Holtås, S.

Proton MR Spectroscopy and Preoperative Diagnostic Accuracy: An Evaluation of Intracranial Mass Lesions Characterized by Stereotactic Biopsy Findings

Isabella Maria Burtscher^,a, Gunnar Skagerberg^a, Bo Geijer^a, Elisabet Englund^a, Freddy Ståhlberg^a and Stig Holtås^a

^a From the Departments of Radiology (I.M.B., B.G., F.S., S.H.), Neurosurgery (G.S.), Pathology (E.E.), and Radiation Physics (F.S.), University Hospital, Lund, Sweden.

View larger version (87K): [in a new window]   FIG 1. A–G, Patient with a pineocytoma: six MR spectra (A–F) represent voxels outlined on the axial, contrast-enhanced T1-weighted MR image (G). Only voxels covering contrast-enhancing parts of the lesion showed pathologic MR spectra.

View larger version (106K): [in a new window]   FIG 2. A–Q, Patient with a cystic high-grade glioma: the images show the heterogeneity of spectra across the lesion. A is an axial, contrast-enhanced T1-weighted MR image with the measurement area and voxels represented by the MR spectra in B–Q outlined; B–I represent voxels in the vertical row (top to bottom) and (J–Q) represent voxels in the horizontal row (left to right). The spectrum representing the intersection of the vertical and horizontal rows is shown twice (H and P)

View larger version (62K): [in a new window]

View larger version (16K): [in a new window]   FIG 3. Scattergram of signal ratios in stereotactic biopsy target points for different tumor types. LA = low-grade astrocytoma (n = 4), HA = high-grade astrocytoma (n = 11), LY = lymphoma (n = 3)

View larger version (235K): [in a new window]   FIG 4. MR spectroscopic scout images and corresponding spectra represent the stereotactic biopsy target points in a high-grade (A and B) and a low-grade (C and D) astrocytoma. The two spectra are almost identical, and signal ratios could not be used to grade the tumors