AJDRAJNR - American Journal of Neuroradiology

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Using 80 kVp versus 120 kVp in Perfusion CT Measurement of Regional Cerebral Blood Flow

Max Wintermarka, Philippe Maedera, Francis R. Verduna, Jean-Philippe Thirana, Jean-François Valleya, Pierre Schnydera and Reto Meulia,b

a From the Department of Diagnostic and Interventional Radiology (M.W., P.M., P.S., R.M.), University Hospital, 1011 Lausanne, Switzerland ; the Institute of Applied Radiophysics (F.R.V., J-F.V.), Grand-Pré 1, 1007 Lausanne, Switzerland; and the Signal Processing Laboratory (J-P.T.), Swiss Federal Institute of Technology, 1015 Lausanne, Switzerland.
b Address reprint requests to Reto Meuli, Associate Professor, Department of Diagnostic and Interventional Radiology, University Hospital, CHUV—BH10, 1011 Lausanne, Switzerland.



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FIG 1. Four cerebral CT sections through the basal nuclei obtained at 200 mAs and at 80 kVp (C, D) and 120 kVp (A, B), before (A, C) and after (B, D) IV administration of iodinated contrast material (C, 80 kVp [number 2], A, 120 kVp [number 1], D, 80 kVp + C [number 4], B, 120 kVp + C [number 3]). ROIs were drawn on cortical gray matter, basal nuclei gray matter, and white matter. Typical ROIs chosen for measurements are shown on A. The four sections are displayed with the same window settings (window level: 40 HU, and window width: 80 HU). At 80 kVp, the contrast enhancement is increased, as well as the gray matter-white matter contrast. The signal-to-noise ratio is not significantly altered