Antenatal Diagnosis of Subependymal Heterotopia
L. Anne Mitchella,
Erin M. Simona,
Roy A. Fillya and
A. James Barkovich
,a
a From the Department of Radiology (L.A.M., E.M.S., R.A.F., A.J.B.), University of California, San Francisco, San Francisco, CA, and the Department of Radiology (L.A.M.), Austin and Repatriation Medical Centre, Melbourne, Australia.
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FIG 1. Images from the case of a 42-year-old pregnant woman who was referred for detailed fetal morphologic sonographic assessment after previous routine sonography suggested Dandy-Walker malformation.
A, Fetal sonogram obtained at 23 weeks' gestation. Axial image, obtained through the upper aspect of the lateral ventricles, shows an irregular ventricular wall with very small hyperechoic nodules along the lateral ventricular walls (arrows).
B, Fetal sonogram obtained at 23 weeks' gestation. Axial image, obtained through the posterior fossa, shows the large cisterna magna (arrows).
C, Axial single-shot fast spin-echo (21901/93/0.5) image shows the lateral ventricles of the fetal brain at 23 weeks' gestation. The lateral ventricular wall is slightly irregular because of the presence of tiny subependymal nodules isointense to the cortex that project into the ventricular lumen (arrows).
D, Axial spin-echo (3000/120) image, obtained 2 months after birth through the lateral ventricles at a level similar to that shown in C, shows multiple subependymal heterotopic nodules that are isointense to gray matter (arrows), corresponding to the nodules seen on the fetal MR image.
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