AJDRAJNR - American Journal of Neuroradiology

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Intraosseous Hematoma in a Newborn with Factor VIII Deficiency

Alan Reevesa and Mary Edwards-Browna

a From the Riley Hospital for Children, Indianapolis.



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FIG 1. Images from the case of a 2-month-old white male patient who was initially seen in a general pediatric clinic for evaluation of bruised and swollen hands.

A, CT scan of the skull shows a large lytic lesion of the right parietal bone, with expansion and scalloping of the bony margins. The patient had a known factor VIII deficiency, and a cephalohematoma was present at birth.

B, T1-weighted MR image of the lytic lesion present on the CT scan shows a bright signal, characteristic for methemoglobin. This indicated that the mass lesion in the skull was secondary to hemorrhage rather than an intraosseous tumor.

C, CT scan obtained 15 weeks after the initial CT scans shows significant bone remodeling and near resolution of the intraosseous hematoma.