The CT and MR Imaging Features of Carcinoma Arising in Thyroglossal Duct Remnants
Christine M. Glastonbury
,a,
H. Christian Davidsona,
Jeffrey R. Hallera and
H. Ric Harnsbergera
a From the Departments of Radiology (C.M.G., H.C.D., H.R.H.) and Otorhinolaryngology (J.R.H.), University of Utah, Salt Lake City, UT.

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FIG 1. TDCa in a 36-year-old man with an enlarging, painless right neck mass and a mass at the level of the hyoid bone.
A, Axial contrast-enhanced CT scan shows a 3 x 2.5-cm jugulodigastric node (arrow), which was shown by fine-needle aspiration to be papillary carcinoma.
B, More inferior CT section shows a solid soft-tissue mass at the level of the hyoid bone, slightly to the right of midline (arrow), representing the primary thyroglossal duct tumor. The thyroid gland was normally positioned.
FIG 2. A 53-year-old man presented with an enlarging midline neck mass. Axial contrast-enhanced CT scan shows both a cystic component containing a fluid-fluid level (arrowhead) and a large, irregular, invasive solid component (arrow). This was determined to be papillary carcinoma arising in a TDC.
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FIG 3. A 56-year-old man presented with a neck mass that had rapidly enlarged over several months. Malignancy was suspected because of heterogeneity, with solid components seen on MR images and sonograms (not shown). Contrast material was not administered. The lesion proved to be inflammatory changes superimposed on a TDC, with no malignancy found at resection.
A, Sagittal T1-weighted MR image shows a heterogeneous mass of slightly hyperintense signal.
B, Axial T2-weighted image shows hyperintense but heterogeneous signal within this complex lesion.
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FIG 4. A 47-year-old woman underwent imaging for a newly detected midline neck mass. An unenhanced axial CT scan shows a 2 x 2-cm cystic mass containing an eccentrically positioned solid nodule with an associated focus of calcification (arrow). The nodule enhanced with contrast material, and pathologic analysis confirmed it to be papillary carcinoma.FIG 5. A 30-year-old woman presented with an enlarging anterior neck mass that at surgery was found to be a TDC with a nodule of papillary carcinoma. The sagittal T2-weighted MR image shows an infrahyoid multiloculated cystic mass with a solid component superiorly (arrow). The locules were of variable T2 and T1 intensity (not shown)
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