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Localized Proton MR Spectroscopy of the Allocortex and Isocortex in Healthy Children

Choong-Gon ChoiGo,a, Tae-Sung Koa, Ho Kyu Leea, Jung Hee Leea and Dae Chul Suha

a From the Departments of Radiology (C-G.C., H.K.L., D.C.S.) and Pediatric Neurology (T-S.K.), Asan Medical Center, University of Ulsan College of Medicine; and the Department of Radiological Science, Asan Institute for Life Sciences (J.H.L.), Seoul, Korea.



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FIG 1. A and B, Coronal (A) and axial (B) T2-weighted MR images show typical locations selected for proton MR spectroscopy of the allocortex (A), parietal cortex, and frontal cortex (B)



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FIG 2. A–C, Typical proton MR spectra obtained from the allocortex (A), parietal cortex (B), and frontal cortex (C). Acquisition and processing parameters used for all spectra are the same as described in the text, except for voxel sizes, which are 5.0 mL for the allocortex and 7.2 mL for the isocortex. All spectra are scaled individually and cannot be used for direct comparison. NAA, 2.01 ppm; Cr, 3.03 ppm; Cho, 3.22 ppm; mI, 3.56 ppm



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FIG 3. Spectroscopic data plotted against age of the children.

A, NAA/Cr vs. age.

B, Cho/Cr vs. age.

C, mI/Cr vs. age.