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Granulomatous Hypophysitis due to Wegener's Granulomatosis

Mayank Goyala, Walter KucharczykGo,a and Edward Keystonea

a From the Departments of Medical Imaging (M.G., W.K.) and Medicine (E.K.), University of Toronto, Toronto, Ontario, Canada.



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  		FIG 1. MR images obtained through the pituitary gland show diffuse enlargement of the pituitary gland. The gland shows diffuse heterogeneous enhancement that extends to the optic chiasm (arrow). Also note the presence of mucosal thickening in the bilateral sphenoid sinus.

A, T1-weighted coronal (450/15/4 [TR/TE/excitations]) MR image.

B, T2-weighted coronal (4000/90/3; echo train length, 8) MR image.

C, Contrast-enhanced T1-weighted coronal (450/15/4) MR image.

D, Contrast-enhanced T1-weight sagittal (450/15/4) MR image.



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  		FIG 2. Follow-up MR examination after 6-week administration of steroids. Contrast-enhanced T1-weighted coronal (450/15/4) MR image shows dramatic resolution in the size of the pituitary gland. No enhancement is seen in the optic chiasm





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X