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Abnormal White Matter Signal in Ataxia Telangiectasia

John J. CieminsGo,a and Alfred L. Horowitza

a From the Department of Radiology, Resurrection Medical Center, Chicago, IL.



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FIG 1. Images from the case of a 31-year-old woman with a 20-year history of ataxia telangiectasia who was admitted to the hospital after complaining of dizziness, headaches, and mood changes.

A, Spin-echo sagittal T1-weighted (600/20/1 [TR/TE/excitations]) MR image shows cerebellar atrophy.

B, Spin-echo axial T1-weighted (600/20/1) MR image shows multiple hypointense foci in the white matter bilaterally.

C, Spin-echo axial T2-weighted (2900/80/1) MR image shows multiple hypointense foci in the white matter bilaterally.