Ganglioglioma of the Optic Chiasm: Case Report and Review of the Literature
Shanop Shuangshotia,
Eberhard Kirscha,
Paul Bannana and
Victoria A. Fabian
,a
a From the Departments of Neuropathology (S.S., V.A.F.), Radiology (E.K.), and Surgery (P.B.), Royal Perth Hospital, GPO Box X2213, Perth, Western Australia, and the Department of Pathology (S.S.), Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
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FIG 1. Images from the case of a 21-year-old woman who presented with mild galactorrhea and emotional instability.
A, Coronal, unenhanced, T1-weighted (500/20/3 [TR/TE/excitations) MR image.
B, Contrast-enhanced sagittal image shows a mass with cystic (white arrow) and nodular contrast-enhancing (black arrow) components arising in the hypothalamus and optic chiasm.
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FIG 2. Images from the same case, obtained 18 months later.
A, Coronal T2-weighted (3300/96/1) MR image.
B, Contrast-enhanced sagittal T1-weighted (500/20/3) MR image shows an obvious progression of the cystic tumor component (black arrows).
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FIG 3. Cytological smear preparation of the ganglioglioma.
A, Abnormal binucleate neurons (hematoxylin and eosin; original magnification, x275).
B, Abnormal binucleate neurons (hematoxylin and eosin; original magnification, x430).
C, Abnormal binucleate neurons (hematoxylin and eosin; original magnification, x275).
D, Neoplastic astrocytes with their numerous cytoplasmic processes (hematoxylin and eosin; original magnification, x275).
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