AJDRAJNR - American Journal of Neuroradiology

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MR Imaging of the Corpus Callosum in Pediatric Patients with Neurofibromatosis Type 1

Elizabeth C. DubovskyGo,a, Tim N. Bootha, Gilbert Vezinaa, Carole A. Samango-Sprousea, Kathryn M. Palmera and Cynthia O. Brasseuxa

a From the Departments of Diagnostic Imaging and Radiology (E.C.D., L.G.V.) and Developmental Pediatrics (C.A.S-S.) and the Children's Research Institute (C.O.B.), Children's National Medical Center, Washington, D.C.; the Department of Radiology (T.N.B.), Dallas Children's Hospital, Dallas, TX; and the Department of Radiology (K.M.P.), Arlington Hospital, Arlington, VA.



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FIG 1. A, Midsagittal T1-weighted image of a 6-year-old patient with NF-1.

B, Midsagittal T1-weighted image of a 6-year-old control patient.



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FIG 2. A, Midsagittal T1-weighted image of a 3-year-old patient with NF-1. The outer contour of the corpus caliosum has been traced. Note is made of a small chiasmatic glioma.

B, The inner contour of the skull has been traced.



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FIG 3. CC and MISS measurements for the control and NF-1 patient populations.

A, Mean CC for control group, by age.

B, Mean CC for NF-1 group, by age.

C, Mean MISS for control group, by age.

D, Mean MISS for NF-1 group, by age.

E, CC/MISS for control group, by age.

F, CC/MISS for NF-1 group, by age.