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AJNR - American Journal of Neuroradiology

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Elastase-Induced Saccular Aneurysms in Rabbits: Comparison of Geometric Features with Those of Human Aneurysms

John G. Short^a, Naomi H. Fujiwara^a, William F. Marx^a, Gregory A. Helm^a, Harry J. Cloft^a and David F. Kallmes^a

^a From the Departments of Radiology (J.G.S., N.H.F., W.F.M., D.F.K.) and Neurosurgery (G.A.H.), University of Virginia Health Services, Charlottesville; and the Department of Radiology, Emory University Hospital, Atlanta, GA (H.J.C.).

View larger version (105K): [in a new window]   FIG 1. A–D, Digital subtraction angiograms in a rabbit 2 weeks after experimental aneurysm creation. The method of measurement of the aneurysm width (A), height (B), parent artery (C), and neck (D) is demonstrated

View larger version (39K): [in a new window]   FIG 2. Graph shows range of dome sizes of experimental aneurysms

View larger version (148K): [in a new window]   FIG 3. A–D, Digital subtraction angiograms show an experimental aneurysm in a rabbit before (A) and after (B) GDC placement. Note the similarity to a human ophthalmic segment aneurysm before (C) and after (D) GDC placement