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AJNR - American Journal of Neuroradiology

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Optic Pathway Glioma: Correlation of Imaging Findings with the Presence of Neurofibromatosis

Liora Kornreich^a, Susan Blaser^a, Michael Schwarz^a, Avinoam Shuper^a, Tal H. Vishne^a, Ian J. Cohen^a, Ricardo Faingold^a, Shalom Michovitz^a, Benjamin Koplewitz^a and Gadi Horev^a

^a From the Department of Imaging (L.K., M.S., G.H.) and the Center for Hematology-Oncology (A.S., I.J.C.), Schneider Children's Medical Center of Israel, Petah Tiqva, Israel; the Department of Imaging, Hospital for Sick Children, Toronto, Canada (S.B., R.F.); the Departments of Surgery (T.H.V.) and Neurosurgery (S.M.), Rabin Medical Center, Petah Tiqva, Israel; and the Department of Imaging, Hadassa Hospital, Jerusalem, Israel (B.K.).

View larger version (93K): [in a new window]   FIG 1. 14-year-old boy with NF. A and B, Sagittal unenhanced (A) and coronal contrast-enhanced (B) T1-weighted MR images show typical findings of OPG in patients with NF: thickened retroorbital optic nerves and chiasm, with preservation of original contour. The tumor is small and homogeneous, without any cystic components

View larger version (138K): [in a new window]   FIG 2. 4-year-old girl without NF. Axial contrast-enhanced T1-weighted image shows typical findings of optic glioma in patients with NF: a large mass, with cystic components, that does not respect the boundaries of the optic pathways. The temporal horns are enlarged, and the right middle cerebral artery courses in a fissure of the mass (arrow)