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AJNR - American Journal of Neuroradiology

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Diffusion Tensor Imaging of Patients with HIV and Normal-appearing White Matter on MR Images of the Brain

Christopher G. Filippi^,a, Aziz M. Ulu^a, Elizabeth Ryan^a, Steven J. Ferrando^a and Wilfred van Gorp^a

^a From the Departments of Radiology (C.G.F., A.M.U.), Psychology (E.R., W.v.G.), and Psychiatry (S.J.F.), New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, NY.

View larger version (35K): [in a new window]   FIG 1. Voxel placements are shown on the diffusion tensor sequence for the determination of the average diffusion constant (Dav).FIG 2. Graph plots values for the anisotropy in the genu and splenium of the corpus callosum versus the measured peripheral viral load levels (HIV messenger RNA copies/mm3). An inverse trend is observed. As the viral load levels increase, the anisotropy of these structures decreases