Diffusion Anisotropy of the Internal Capsule and the Corona Radiata in Association with Stroke and Tumors as Measured by Diffusion-weighted MR Imaging
Shuichi Higanoa,
Jianhui Zhonga,
David A. Shriera,
Dean K. Shibataa,
Yukinori Takasea,
Henry Wanga and
Yuji Numaguchi
,a
a From the Department of Radiology (S.H., J.Z., D.A.S., D.K.S., Y.T., H.W., Y.N.), Division of Neuroradiology, University of Rochester Medical Center, Rochester, NY.
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FIG 1. Screen of defining ROI. The DAV image (upper left), the ASD map image (lower left), and the Dz image (lower right) were displayed on the screen, and the location of the defined ROI were shown on the three images simultaneously
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FIG 2. Mean and SD of AI(ASD) of the internal capsule or the corona radiata involved by various types of lesions. Analysis of variance, F = 39.6; P < .0001; Post hoc test (Scheffe); *, P = .05 as compared with the control group; **, P < .0001 as compared with both control and uninvolved groups
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FIG 3. Acute cerebral infarction of the right corona radiata with moderate-severe left hemiparesis.
A, T2-weighted echo-planar image (b = 0) shows an oval hyperintense lesion involving the right corona radiata.
B, Apparent diffusion coefficient image shows a decreased diffusion coefficient in the lesion.
C, In the ASD image, the diffusion anisotropy is also reduced.
D, T2-weighted echo-planar image (10000/98 [TR/TEeff]) that includes the internal capsule shows no involvement of the right internal capsule, although high intensity spotty lesions were noted in the bilateral lentiform nuclei.
E, Apparent diffusion coefficient image of the same section as that shown in D shows no definite abnormality in the internal capsule.
F, ASD image shows decreased diffusion anisotropy in the posterior limb of the right internal capsule as compared with the left side.
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FIG 4. Glioblastoma involving the right corona radiata and basal ganglia with moderate-severe hemiparesis.
A, T2-weighted echo-planar image shows an irregular mass with marked perifocal edema involving the right corona radiata.
B, Apparent diffusion coefficient image shows an irregular mass with marked perifocal edema involving the right corona radiata.
C, In the ASD image, the diffusion anisotropy of the right corona radiata is hardly noted.
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FIG 5. Mean and SD of AI(ASD) of the internal capsule or the corona radiata for each degree of hemiparesis. Analysis of variance, F = 17.0; P < .0001; Post hoc test (Bonferroni); *, P < .0001 as compared with every other group
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FIG 6. Comparison of AI(ASD) value (mean and SD) of normal-appearing internal capsule and corona radiata between the patients with entirely intact corticospinal tract (Intact) and those having some involved segments of the corticospinal tract (Involved)
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