Children with Macrocrania: Clinical and Imaging Predictors of Disorders Requiring Surgery
L. Santiago Medina
,a,
Kieran Frawleya,
David Zurakowskia,
Dina Buttrosa,
Antonius J.C. DeGrauwa and
Kerry R. Cronea
a From the Health Outcomes and Policy Section (L.S.M., K.F.), Radiology Outcomes Center, Department of Radiology, Children's Hospital Medical Center, Cincinnati, OH, the Harvard Medical School, Children's Hospital (D.Z.), Boston, MA, and the Department of Neurology (D.B., A.J.C.D.) and Division of Neurosurgery (K.R.C.), Children's Hospital Medical Center, Cincinnati, OH.

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FIG 1. Comparison of receiver operating characteristic curves of four independent clinical predictors versus a combination of these clinical predictors plus two independent imaging predictors. The diagnostic performance, as illustrated by the area under the curve, was greater for the combination of clinical and imaging predictors than for clinical predictors alone, although the difference was not statistically significant (P = .09)
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