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Prenatal Diagnosis and Postnatal Follow-up of Pericallosal Lipoma: Report of Seven New Cases

Valérie Ickowitza, Danièle Eurina, Françoise Rypensa, Pascale Sonigoa, Isabelle Simona, Phillipe Davida, Francis Brunellea and Fred E. AvniGo,a

a From the Department of Pediatric Imaging, Charles Nicolle Hospital (V.I., D.E.), Rouen, France; the Department of Pediatric Imaging, Erasme Hospital (F.R., P.D., F.E.A.), University Clinics of Brussels, Brussels, Belgium; the Department of Pediatric Imaging (P.S., I.S., F.B.), Hôpital des Enfants Malades, Paris, France; and the Department of Pediatric Imaging, University Children's Hospital Queen Fabiola (F.E.A.), Brussels, Belgium.



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FIG 1. Tubulo-nodular type of pericallosal lipoma. In utero and postnatal follow-up images (case 3).

A, Sonogram obtained in utero at 35 weeks' gestation. A biparietal image is shown. A hyperechoic mass (M) can be seen within the anterior midline. The lipoma appears slightly less echogenic than the parietal bone; its margins are irregular. The mass is extending toward the frontal lobes (arrows).

B, MR image obtained at birth. Sagittal view turbo spin-echo T1-weighted image (350/16/1) confirms the presence of the lipoma and the agenesis of the corpus callosum.

C, MR image obtained at birth. Frontal view turbo spin-echo T1-weighted image (350/16/1) shows the lateral extend of the lipoma.

D, MR image obtained at age 3 years. Mid-sagittal view turbo spin-echo T1-weighted sequence (450/15/1) shows the growth of the lipoma.

E, MR image obtained at age 3 years. Similar findings are revealed by the frontal view turbo spin-echo T1-weighted sequence (450/15/1).



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FIG 2. Tubulo-nodular type. Fetal MR images (case 4).

A, Mid-sagittal view turbo spin-echo T1-weighted sequence (400/17/1) shows typical lipoma and incomplete corpus callosum. Note that it was not possible to obtain this sagittal view image by using obstetric sonography.

B, Transverse turbo spin-echo T1-weighted sequence (400/17/1) shows the lipoma and the extension toward the plexus choroids.



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FIG 3. Curvilinear pattern. Sonograms and fetal MR images (case 7).

A, Obstetric sonograms obtained 26.5 weeks. Sagittal view image of the fetal head. The lipoma appears as a hyperechoic mass (arrowheads) with smooth margins parallel to the corpus callosum (arrow).

B, Fetal MR image. Mid-sagittal fast spin-echo T2-weighted sequence (8000/122/2) shows a curvilinear hyposignal lipoma and a normal corpus callosum.