AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Messori, A.
Right arrow Articles by Salvolini, U.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Messori, A.
Right arrow Articles by Salvolini, U.

An Unusual Spinal Presentation of Whipple Disease

Anna Messoria, Paolo Di Bellaa, Gabriele Polonaraa, Francesco Logulloa, Paola Pauria, Ramazan Haghighipoura and Ugo SalvoliniGo,a

a From the Departments of Neuroradiology (A.M., G.P., U.S.), Neurology (P.D.B., F.L., R.H.), and Microbiology (P.P.), University of Ancona, Italy.



View larger version (91K):

[in a new window]
  		FIG 1. August 1994. Sagittal fast spin-echo T2-weighted (5000/112/2) (TR/TE/excitations) image shows enlarged and inhomogeneously hyperintense spinal cord from the cervico-occipital junction to the upper dorsal region (A). Sagittal spin-echo T1-weighted (460/17/2) images with gadopentate dimeglumine show peripherical enhancement (B). After seven days of corticosteroid therapy, spinal cord enlargement has decreased (C). Eight months later (April 1995), the cord is normal (D)



View larger version (98K):

[in a new window]
  		FIG 2. November 1995. Sagittal T2-weighted (5000/112/2) image shows enlarged and inhomogeneously hyperintense spinal cord from distal cervical to upper thoracic cord (A). One month later, the cord is normal (B)



View larger version (114K):

[in a new window]
  		FIG 3. May 1997. Coronal fast-FLAIR (9002/137/2000) (TR/TE/TI) image shows nodular signal hyperintensity with slight mass effect in left middle cerebellar peduncle.

FIG 4. December 1997. Axial fast spin-echo T2-weighted (2300/85/1) (A) and enhanced spin-echo T1-weighted (500/14/1) images (B and C) show hyperintense and enhancing lesions in both middle cerebellar peduncles, in left superior cerebellar peduncle, and in left inferior quadrigeminal colliculus



View larger version (110K):

[in a new window]
  		FIG 5. March 1998. Coronal fast-FLAIR (9002/137/2000) images show persistence of the lesions observed previously (A), increased involvement of middle and new involvement of superior right cerebellar peduncles (B)



View larger version (107K):

[in a new window]
  		FIG 6. January 2000 (5 months after start of antibiotic therapy). Coronal fast-FLAIR (8802/105/2200) images show regression: only slight signal abnormalities in the structures previously involved, and no new lesions





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X