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Intracranial Giant Cell Reparative Granuloma Arising from the Temporal Lobe Area: MR Findings

T. Lucien Mohammeda, David P. Brummetta, Francis J. HahnGo,a and Poonam Sharmaa

a From the Departments of Diagnostic Radiology (T.L.M., D.P.B., F.J.H.) and Pathology (P.S.), University of Nebraska Medical Center, Omaha, NE.



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  		FIG 1. A, Axial T1-weighted MR image 9400/19/2 [TR/TE/excitations]). An isointense septated extraaxial mass in the left temporal fossa.

B, Axial postcontrast T1-weighted MR image (650/11/2). Well-encapsulated mass with contrast enhancement of the capsule and septations.

C, Coronal postcontrast T1-weighted MR image (650/11/2). Extraaxial mass effect on the adjacent brain parenchyma is seen.

D, Axial T2-weighted MR image (3500/102/2). The mass is hyperintense on the T2-weighted image without associated edema



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  		FIG 2. A, Low-power microscopic section of the tumor shows randomly distributed multinucleated giant cells in spindle cell stroma (hematoxylin and eosin staining, magnification x100).

B, High-power microscopic section with numerous multinucleated giant cells (hematoxylin and eosin staining, magnification x400)



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  		FIG 3. A 12-month posttherapy CT scan with bone windows (3000/650) shows postoperative changes at the left temporal bone without evidence of tumor recurrence





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X