AJDRAJNR - American Journal of Neuroradiology

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Parasagittal Ependymoma Resembling Falcine Meningioma

Andrew S. Youkilisa, Paul Parka, Paul E. McKeevera and William F. Chandlera

a From the Department of Neurosurgery (A.S.Y., P.P., W.F.C.), and the Department of Pathology (P.E.M.), University of Michigan Medical Center, Ann Arbor, MI.



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FIG 1. A, Sagittal T1-weighted precontrast MR imaging at 580/18 (TR/TE) and B, axial T1-weighted postcontrast MR imaging at 720/20 (TR/TE) reveal parafalcine mass with heterogeneous contrast enhancement and dense calcification laterally. Asterisk in B indicates contrast-enhancing dural tail



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FIG 2. Coronal, T1-weighted, postcontrast MR imaging at 850/22 (TR/TE) further delineates parasagittal mass. Curved arrow points to region of dense calcification.FIG 3. Axial T2-weighted MR imaging at 2500/80 (TR/TE) reveals dense mineralization in lateral aspect of mass. High cerebrospinal fluid signal surrounding mass emphasizes extraparenchymal nature of lesion



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FIG 4. A, GFAP highlights intensely positive glial fibrils in perivascular rosettes. Other cells have clear cytoplasm. Nuclei are round and oval with finely speckled chromatin.

Plus sign is in vessel lumen; solid arrow points to perivascular GFAP positivity.

B, Groups of vacuolated cells are positive for GFAP (open curved arrow) and spread between a hyalinized matrix (solid arrow).

C, MIB-1 proliferation index is focally high, up to 18%.