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Detection of Mesial Temporal Lobe Hypoperfusion in Patients with Temporal Lobe Epilepsy by Use of Arterial Spin Labeled Perfusion MR Imaging

Ronald L. Wolfa, David C. Alsopa, Igor Levy-Reisa, Philipp T. Meyera, Joseph A. Maldjiana, Julio Gonzalez-Atavalesa, Jaqueline A. Frencha, Abass Alavia and John A. Detrea

a >>From the Departments of Radiology (R.L.W., D.C.A., P.T.M., J.A.M., A.A.) and Neurology (I.L.-R., J.G.-A., J.A.F., J.A.D.), University of Pennsylvania Medical Center, Philadelphia, PA.



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  		FIG 1. Data acquired from a patient with left temporal lobe epilepsy (patient 8).

A, T1-weighted axial images (600/14) show a representative mTL ROI used for calculation of mTL perfusion.

B, Continuous ASL perfusion images obtained at the same anatomic levels show hypoperfusion in the anterior left mTL (white arrow).

C, 18FDG-PET images obtained at approximately the same anatomic levels show hypometabolism in the left mesial temporal structures compared with the right (black arrow).





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X