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Demonstration of Glycine Peaks at 3.50 ppm in a Patient with van der Knaap Syndrome

R. Nuri Senera

a From the Department of Radiology, Ege University Hospital, Bornova, Izmir, 35100, Turkey.



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  		FIG 1. Proton MR spectrum of pure glycine, recorded using a laboratory spectrometer with a 9.397-T magnet, reveals the peak at 3.52 ppm



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  		FIG 2. 14-month-old boy with van der Knaap syndrome.

A, FLAIR image shows widespread signal abnormality and characteristic cystic degeneration of the white matter in the right temporal lobe.

B, Spectrum obtained at 1500/40 (TR/TE) in a voxel from the left hemisphere reveals that the most prominent peak belongs to glycine, at 3.50 ppm (long arrow). Note that to the left of the glycine peak is that of myo-inositol, at 3.56 ppm (short arrow).





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X