Intracranial and Spinal MR Imaging Findings Associated with Krabbe's Disease: Case Report
Curtis A. Given IIa,
Cesar C. Santosa and
David D. Durdena
a From the Departments of Neuroradiology (C.A.G., D.D.D.) and Neurology (C.C.S.), Wake Forest University Baptist Medical Center, Winston-Salem, NC.
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FIG 1.
Axial view T2-weighted MR image (4200/90 [TR/TE]) reveals symmetric areas of T2 prolongation (arrows) within the centrum semiovale
FIG 2. Coronal view fluid-attenuated inversion recovery image (8002/137.5) reveals symmetric areas of abnormal signal intensity (arrows) within the periventricular white matter
FIG 3. Coronal view T1-weighted image (400/20) obtained after the IV administration of contrast material reveals no enhancement within the periventricular white matter (arrows)
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FIG 4. T1-weighted MR images (450/20) of the lumbosacral region reveal striking contrast enhancement of the lumbosacral nerve roots (arrows).
A, Sagittal view.
B, Axial view.
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FIG 5. T2-weighted MR images (4000/105) display normal signal intensity within the substance of the spinal cord and lumbosacral nerve roots.
A, Sagittal view.
B, Axial view.
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AJNR - American Journal of Neuroradiology