AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kallmes, D. F.
Right arrow Articles by Cloft, H. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kallmes, D. F.
Right arrow Articles by Cloft, H. J.

Elastase-Induced Saccular Aneurysms in Rabbits: A Dose-Escalation Study

David F. Kallmesa, Naomi H. Fujiwaraa, Stuart S. Berra, Gregory A. Helmb and Harry J. Cloftc

a Department of Radiology, University of Virginia Health Services, Charlottesville
b Department of Neurosurgery, University of Virginia Health Services, Charlottesville
c Department of Radiology, Emory University Hospital, Atlanta, GA



View larger version (32K):

[in a new window]
  		FIG 1. Bar graph shows a summary of the mean dimensions.



View larger version (100K):

[in a new window]
  		FIG 2. Intravenous digital subtraction angiograms, anteroposterior views, obtained in animals from each group.

A, Sham group, 4 weeks after surgery. No aneurysm cavity is present at the stump of the right CCA (arrowhead). The parent artery (curved arrow) is not significantly dilated. Contrast enhancement within the persistent left superior vena cava is darker than arterial contrast enhancement because of stasis in the venous structure (straight arrow).

B–D, Low-dose (25% elastase, 10 minutes) (B), medium-dose (50% elastase, 10 minutes) (C), and high-dose (50% elastase, 10 minutes) (D) groups, 21 days after surgery. Brachiocephalic arteries are opacified, including the left CCA (open arrow); right subclavian artery (straight solid arrow); and aneurysm cavity, ie, aneurysmal dilatation of the right CCA origin (arrowhead). In B, the parent artery (curved solid arrow) is not dilated. In C, the parent artery (curved solid arrow) is slightly dilated compared with that in A and B. In D, the proximal and distal parent arteries (curved solid arrow) are remarkably dilated compared with those in A and B.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X