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AJNR - American Journal of Neuroradiology

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Multiple Myeloma Involving the Thyroid Cartilage: Case Report

Jacob Sosna^a,d, B. Simon Slasky^a, Ora Paltiel^b, Galina Pizov^c and Eugene Libson^a

^a Department of Radiology, Hadassah Hebrew University Hospital, Jerusalem, Israel
^b Department of Hematology, Hadassah Hebrew University Hospital, Jerusalem, Israel
^c Department of Pathology, Hadassah Hebrew University Hospital, Jerusalem, Israel
^d Department of Radiology, Beth-Israel Deaconess Medical Center, Boston, MA

View larger version (103K): [in a new window]   FIG 1. Lateral scout view of the neck in a 54-year-old man with multiple myeloma of the thyroid cartilage shows a mass containing numerous calcifications in the region of the thyroid cartilage, with compression and narrowing of the larynx and upper trachea (arrow).

View larger version (103K): [in a new window]   FIG 2. Axial CT scans obtained through the upper cervical region. The thyroid cartilage is enlarged bilaterally, with conglomerates of coarse calcifications, mainly in the central area and more evident on the right.

View larger version (103K): [in a new window]   FIG 3. Immunohistochemical specimen. Diffuse infiltration with myeloma plasma cells. With immunohistochemistry, positive staining to the kappa light chain was noted. No amyloid was found (Hematoxylin-Eosin, original magnification x10).