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MR Imaging Characteristics of Amyloid Deposits in Pituitary Adenoma

Steven W. Martina, Daniel R. Leftona, Richard S. Pintoa, Marc Rosenblumb and Eric Elowitza

a Beth Israel Medical Center, New York, NY
b Memorial Sloan-Kettering Cancer Center, New York, NY



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  		FIG 1. MR imaging of a mass arising from the pituitary gland.

A and B, Coronal T1-weighted images of the sella turcica before (A) and after (B) intravenous contrast agent administration shows an enlarged pituitary gland with expansion of the sella and enhancing intratumoral septations.

C, Axial T2-weighted image through the pituitary shows decreased T2 signal intensity relative to gray and white matter.



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  		FIG 2. Nodular amyloid deposits are shown as lobulated masses of eosinophilic material with a peripheral, concentric, and ringlike substructure. Cholesterol clefts are seen in the adjacent stroma (hematoxylin-eosin stain, original magnification x40).





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X