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Diffusion-Weighted Imaging in a Patient with Vertebral and Epidural Abscesses

James D. Eastwooda, Robin T. Vollmerb and James M. Provenzalea

a Department of Radiology, Duke University Medical Center and Durham Veteran’s Affairs Medical Center, NC
b Department of Anatomic Pathology, Durham Veteran’s Affairs Medical Center, NC



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FIG 1. Images obtained in an 83-year-old man with bacteremia and back pain.

A, T2-weighted sagittal MR image (3000/103) shows a small ventral extradural mass (upper arrow) and a fracture and abnormal signal intensity adjacent to the superior endplate of the L1 vertebral body (lower arrow).

B and C, T1-weighted sagittal MR images (815/30) obtained before (B) and after (C) IV administration of gadolinium-based contrast material show central nonenhancement in the extradural mass (long arrow in C) and in a substantial portion of the superior portion of the L1 vertebral body (short arrows in C). Both areas of nonenhancement were interpreted as abscesses.

D, Sagittal diffusion-weighted MR image (1215/80/2, b = 500) obtained at the same location as in AC shows very high signal intensity within the extradural abscess (straight arrow) and high signal intensity within the region of the vertebral abscess (curved arrow).

E, Sagittal diffusion-weighted MR image (1215/80/2) obtained immediately to the left of D shows high signal intensity in the vertebral abscess (arrows).

F, ADC map obtained at same location as in D shows the dark appearance of both epidural (solid arrow) and vertebral abscess (open arrows) regions.



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FIG 2. Images obtained during biopsy of the vertebral body thought to contain an abscess.

A, Transverse CT image obtained at the level of L1 during needle placement for biopsy shows the position of the biopsy needle with the inner stylet at the final position prior to the aspiration of fluid from the bone. The black dot marks the location of the tip of the needle after removal of the inner stylet.

B, Sagittal reformatted image that was constructed from the prebiopsy CT scan. The black dot shows the position of the needle tip shown in A.



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FIG 3. Photomicrograph shows debris and multiple polymorphonuclear leukocytes. The findings were interpreted as being consistent with acute infection (hematoxylin-eosin, original magnification x800).