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Diffusion Tensor MR Imaging of High-Grade Cerebral Gliomas

Saurabh Sinhaa, Mark E. Bastinb, Ian R. Whittlea and Joanna M. Wardlawa

a Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, Scotland
b Department of Medical and Radiological Sciences (Medical Physics), University of Edinburgh, Western General Hospital, Crewe Road, Scotland



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FIG 1. Images in patient 4.

A and B, Contrast-enhanced T1-weighted volume images. In B, the solid arrow indicates a region of an enhancing tumor margin; dashed arrow, enhancing tumor core; dotted arrow, nonenhancing tumor core.

C and D, T2-weighted EP images. Arrow in D indicates a region of edematous brain.

E, <D> parametric map.

F, FA parametric map.



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FIG 2. Images in patient 5.

A, Contrast-enhanced T1-weighted volume image. The solid arrow indicates a region of enhancing tumor margin; dashed arrow, enhancing tumor core; dotted arrow, nonenhancing tumor core.

B, T2-weighted EP images. Arrow indicates a region of edematous brain.

C and D, Note the high <D> and low FA values in the nonenhancing tumor core and edematous brain on the <D> parametric map (C) and FA parametric map (D).



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FIG 3. Images in patient 3. The thick arrow indicates a region of enhancing tumor margin; the thin arrow in B indicates edematous brain.

A, Contrast-enhanced T1-weighted volume image.

B, T2-weighted EP images.

C, <D> parametric map. Note the diffuse nature of the edema.

D, FA parametric map.