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AJNR - American Journal of Neuroradiology

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Radiculomyelitic Rabies: Can MR Imaging Help?

Ravi V. Desai^a, Vivek Jain^b, Paramjeet Singh^a, Sunit Singhi^b and Bishen Dass Radotra^c

^a Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India
^b Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
^c Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

View larger version (136K): [in a new window]   FIG 1. Axial T2-weighted image of the dorsal spine reveals hyperintensity of central gray matter, with sparing of the white matter.

View larger version (89K): [in a new window]   FIG 2. Images show cranial extension to symmetrically involve bilateral thalami, hippocampi, basal ganglia, and the dorsal aspect of the brainstem. A, T2-weighted MR image of the brain, obtained at the level of basal ganglia, reveals hyperintensity of the caudate head and lentiform nucleus. B, T2-weighted MR image of the brain, obtained at the level of the pons, reveals hyperintensity of the posterior portion of the pons.

View larger version (141K): [in a new window]   FIG 3. Perivascular lymphocytic infiltrate and microglial hyperplasia in the cervical cord (hematoxylin and eosin, original magnification x140). Inset shows positive immunostaining using monoclonal anti-rabies antibodies.