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MR Imaging of Leptomeningeal Metastases: Comparison of Three Sequences

Sanjay K. Singha, Norman E. Leedsa and Lawrence E. Ginsberga

a From the Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX



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  		FIG 1. Axial view MR images of a 41-year-old male patient with leptomeningeal metastases from laryngeal squamous cell carcinoma.

A, Unenhanced FLAIR image (10,000/147; inversion time, 2200 ms) shows diffuse abnormal signal intensity in the subarachnoid space (arrowhead).

B, Contrast-enhanced FLAIR image (10,000/147; inversion time, 2200 ms) shows diffuse abnormal signal intensity in the subarachnoid space (arrowheads).

C, Contrast-enhanced T1-weighted MR image (600/8) is falsely negative. Parenchymal metastasis is also identified (arrow).



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  		FIG 2. Axial view MR images of a 59-year-old male patient with leptomeningeal metastases from ependymoma.

A, Unenhanced FLAIR image (10,000/147; inversion time, 2200 ms) appears unremarkable.

B, Contrast-enhanced FLAIR image (10,000/147; inversion time, 2200 ms) appears unremarkable.

C, Contrast-enhanced T1-weighted MR image (600/8) shows enhancement along the surface of the midbrain (arrowheads). Thickened, enhancing dura is also identified on the contrast-enhanced images.



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  		FIG 3. Axial view MR images of a 26-year-old male patient with leptomeningeal metastases from leukemia.

A, Unenhanced FLAIR image (10,000/147; inversion time, 2200 ms) is negative.

B, Contrast-enhanced FLAIR image (10,000/147; inversion time, 2200 ms) is negative.

C, Contrast-enhanced T1-weighted MR image (600/8) shows enhancement along the superior surface of the cerebellum (arrows). Artifact is noted in the right temporal and occipital lobes.





Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X