Quantification of Brain Gray Matter Damage in Different MS Phenotypes by Use of Diffusion Tensor MR Imaging
Marco Bozzalia,
Mara Cercignania,
Maria Pia Sormania,
Giancarlo Comib and
Massimo Filippia
a Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
b Clinical Trials Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

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FIG 1. histograms of the whole patient population, of each clinical subgroup, and of the control volunteers.
A, GM from normal control volunteers (gray line) and whole patient population (black line).
B, GM from patients with RRMS (black line), patients with PPMS (gray line), and patients with SPMS (dotted line).
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