Brain Microhemorrhages Detected on T2*-Weighted Gradient-Echo MR Images
Yoshito Tsushimaa,
Jun Aokib and
Keigo Endob
a Department of Radiology, Motojima General Hospital, Gunma University Hospital, Gunma, Japan
b Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Hospital, Gunma, Japan

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FIG 1. Multiple microhemorrhages were detected.
A and B, T2*-weighted gradient-echo images show microhemorrhages.
C and D, Lesions were less conspicuous on T2-weighted fast spin-echo images and were rarely shown on T1-weighted spin-echo images (not shown).
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FIG 2. Graph shows age distribution (in years) of microhemorrhages. These lesions are usually observed in patients older than 40 years. The incidence of deep microhemorrhages increases with age, but that of lobar microhemorrhages seems to plateau in patients older than 60 years.
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FIG 3. Graph shows correlation between the severity of white matter hyperintensity and the number of microhemorrhages (r = 0.71, P < .00001). Bars indicate SD.
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FIG 4. T2*-weighted gradient-echo image of a 67-year-old hypertensive man who had hemorrhagic stroke at the left lentiform nucleus 2 years previously shows many deep microhemorrhages.
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FIG 5. Graph shows incidence of microhemorrhages in patients with histories of deep and lobar hemorrhagic stroke. The incidence of lobar microhemorrhages is significantly higher in the patients with histories of lobar hemorrhagic stroke (P < .005).
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FIG 6. Images of a 71-year-old man who had multiple lobar (cortical-subcortical) microhemorrhages.
A and B, T2*-weighted gradient-echo images show multiple lobar microhemorrhages (arrows).
C, New hemorrhagic stroke at the left parietal lobe can be seen 34 days after microhemorrhages were first observed on T2*-weighted gradient-echo images.
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FIG 7. Images obtained in a 64-year-old woman who had multiple deep microhemorrhages.
A and B, T2*-weighted gradient-echo images show multiple deep microhemorrhages (arrows).
C, New hemorrhagic stroke at the right caudate head can be seen 402 days after microhemorrhages were first observed on T2*-weighted gradient-echo images.
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