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AJNR - American Journal of Neuroradiology

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Dirty-Appearing White Matter in Multiple Sclerosis: Volumetric MR Imaging and Magnetization Transfer Ratio Histogram Analysis

Yulin Ge^a, Robert I. Grossman^a, James S. Babb^a, Juan He^a and Lois J. Mannon^a

^a From the Department of Radiology, New York University School of Medicine, New York, NY

View larger version (89K): [in a new window]   FIG 1. The PD-weighted scan shows DAWM areas, which are typically located in the periventricular and centrum semiovale regions of white matter in MS patients. A, DAWM with a single plaque. B, DAWM with several plaques. C, pure DAWM without plaques visible. D, outlined DAWM masks from C.

View larger version (21K): [in a new window]   FIG 2. The average MTR histograms were generated from NAWM, DAWM, and lesion plaques. Note that the histogram of DAWM was located between the histograms of NAWM and lesion plaques.