Timing of Cortical Activation: A Latency-Resolved Event-Related Functional MR Imaging Study
Mona A. Mohameda,
David M. Yousema,
Aylin Tekesa,
Nina M. Brownera and
Vince D. Calhounb,c
a Russell H. Morgan Department of Radiology and Radiological Sciences, Division of Neuroradiology, Johns Hopkins Hospital, Baltimore, MD
b Division of Psychiatric Neuro-Imaging, Johns Hopkins Hospital, Baltimore, MD
c Olin Neuropsychiatry Research Center, Institute of Living, Yale University School of Medicine, New Haven, CT
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FIG 1. Statistical activation maps (top left), T1W sections (top right), and render images (bottom left) for the random-effects group analysis (n = 26) showing the visual and motor activations P < .05 (corrected).
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FIG 2. A single subject’s averaged time course of the fMRI % signal intensity change in the visual cortex (RO) by using his amplitude estimate and the group map.
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FIG 3. Mean lower quartile latencies (in seconds ± SEM) by using the group map for 26 subjects.
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FIG 4. Mean lower quartile latencies (in seconds ± SEM) by using the individual maps for the 26 subjects.
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FIG 5. Regression analysis between RT and age.
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FIG 6. Regression analysis between age and the group analysis SMA latency.
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FIG 7. Regression analysis between age and the individual analysis SMA latency.
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