Proton MR Spectroscopy of Polymicrogyria and Heterotopia
Elysa Widjajaa,
Paul D. Griffithsb and
Iain D. Wilkinsonb
a Department of Radiology, Royal Hallamshire Hospital, Sheffield, England
b Academic Unit of Radiology, University of Sheffield, England
View larger version (51K):
[in a new window]
|
FIG 1. Control case.
A, Axial T2-weighted MR image shows the single 2 x 2 x 2-cm voxel (box) localized in frontal lobe white matter from which the proton spectrum was acquired.
B, MR spectrum shows that the Cho and Cr peaks are roughly equal in height, and the N-acetylaspartate (NAA) peak is approximately 1.6 times the height of the Cr peak.
| |
View larger version (49K):
[in a new window]
|
FIG 2. Subcortical heterotopia.
A, Axial T2-weighted MR image shows the sampled region of interest (box) over the area of subcortical heterotopia.
B, MR spectrum shows that the NAA, Cho, and Cr peaks are similar to that of the control case in Figure 1.
| |
View larger version (47K):
[in a new window]
|
FIG 3. Polymicrogyria.
A, Axial T2-weighted MR image shows a region of interest (box) for spectroscopic analysis centered over the area of polymicrogyria in the left frontal lobe.
B, MR spectrum of this lesion shows that the NAA peak is similar to that of normal brain.
| |
AJNR - American Journal of Neuroradiology