AJDRAJNR - American Journal of Neuroradiology

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Inflammatory Myofibroblastic Tumor of the Temporal Bone

Roberto Gasparottia, Diego Zanettib, Andrea Bolzonib, Paola Gambab, Maria L. Morassic and Marco Ungaric

a Department of Radiology, University of Brescia, Brescia, Italy
b Section of Neuroradiology, the Department of Otolaryngology, University of Brescia, Brescia, Italy
c Department of Pathology, University of Brescia, Brescia, Italy



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FIG 1. High resolution bone algorithm CT scans. Erosive expansile lesion of the right temporal bone, involving the mastoid antrum, with complete erosion of the tegmen (short arrows) and partial erosion of the cortex of the lateral semicircular canal (arrowheads) can be seen. The lesion extends throughout the attic, sparing the ossicular chain (long arrow).

A, Axial view.

B, Coronal view.



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FIG 2. MR images.

A, Axial view T2-weighted MR image reveals a low intensity lesion occupying the right mastoid with associated hyperintense debris.

B, Axial view T1-weighted image. The lesion is homogeneously isointense to brain.

C, Coronal view T2-weighted MR image shows infiltration of the otic capsule, but the signal intensity of the lateral and superior semicircular canals is normal.

D, Axial view contrast-enhanced T1-weighted MR image shows homogeneous enhancement of the lesion, with an extensive regular thickening and enhancement of the dura of the convexity and of the right edge of the tentorium (arrowheads).

E, MR venogram shows patency of the right sigmoid sinus, which is slightly reduced in size (arrow).



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FIG 3. Microscopic images.

A, Proliferation of spindle cells oriented in intersecting fascicles or haphazardly distributed, accompanied by numerous plasma cells and small lymphocytes (original magnification, x200).

B, Myofibroblasts show minimal nuclear pleomorphism (original magnification, x1000)