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AJNR - American Journal of Neuroradiology

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MR Imaging Features in Marinesco-Sjögren Syndrome: Severe Cerebellar Atrophy Is Not an Obligatory Finding

Anke Reinhold^a,b, Ianina Scheer^c, Rüdiger Lehmann^d, Luitgard M. Neumann^b, Theodor Michael^a, Raymonda Varon^b and Arpad von Moers^a

^a the Clinic for Pediatric Neurology, Charité Campus Mitte; Berlin, Germany
^b the Institute for Human Genetics, Charité Campus Mitte; Berlin, Germany
^c the Institute for Radiology, Abteilung Pädiatrische Radiologie, Charité Campus Mitte; Berlin, Germany
^d the Charité Campus Virchow; and the Institut für Radiologie, Abteilung Neuroradiologie, Charité Campus Mitte; Berlin, Germany

View larger version (81K): [in a new window]   FIG 1. Sagittal midline T1-weighted MR image shows slight cerebellar atrophy of the superior part of the vermis and no demonstrable posterior pituitary bright spot. The anterior pituitary gland appears small.

View larger version (81K): [in a new window]   FIG 2. Sagittal midline T2-weighted MR image shows that the cerebellomedullary cisterna is enlarged and reaches up to the tentorium. No cerebellar atrophy is observed.