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AJNR - American Journal of Neuroradiology

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Abnormal Brain Diffusivity in Patients with Neuropsychiatric Systemic Lupus Erythematosus

Gerlof P. Th. Bosma^a, Tom W. J. Huizinga^b, Simon P. Mooijaart^a and Mark A. van Buchem^a

^a Department of Radiology, Leiden University Medical Center, the Netherlands
^b Department of Rheumatology, Leiden University Medical Center, the Netherlands

View larger version (11K): [in a new window]   FIG 1. .Mean ADC histograms for patients with a history of NPSLE (NPSLE) and the healthy control subjects (Controls) corrected for brain size. Note the lower peak height and increased number of pixels with higher ADC values in the NPSLE group.

View larger version (12K): [in a new window]   FIG 2. .Uncorrected mean ADC histograms of the 10 control subjects at first-time imaging (Scan 1), at repeat imaging (Scan 2), and at imaging after repositioning (Scan 3). Note the high reproducibility of the ADC histograms.