Minimally Invasive Oxygen-Ozone Therapy for Lumbar Disk Herniation
Cosma F. Andreulab,
Luigi Simonettia,
Fabio de Santisa,
Raffaele Agatia,
Renata Riccia and
Marco Leonardia
a Department of Neuroradiology, Ospedale Bellaria, Bologna, Italy
b Ospedale Policlinico, Bari, Italy

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FIG 1. Puncture at L4-L5 performed under CT guidance.
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FIG 2. Injection of the oxygen-ozone mixture through a millipore filter.
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FIG 3. Therapeutic outcome 6 months after oxygen-ozone therapy. Light gray bars indicate group A (n=300); dark gray bars, group B (n=300). Numbers at top of bars are percentages.
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FIG 4. A, Low-magnification photomicrograph of histologic specimen of the intervertebral disk shows chronic inflammatory infiltrate (hematoxylin & eosin stain; original magnification, x 4).
B, Higher magnification photomicrograph of histologic disk specimen discloses the lymphocytic nature of the infiltrate (hematoxylin & eosin stain; original magnification, x 10).
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