Giant Cell Reparative Granuloma of the Temporal Bone: MR Findings with Pathologic Correlation
Hyun Jeong Kima,
Ho Kyu Leea,
Dae Chul Suha,
Choong Gon Choia,
Jae Kyun Kima,
Jeong Hyun Leea and
Kyung Ja Chob
a Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
b Department of Diagnostic Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
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FIG 1. Images of a 50-year-old man with a 2-year history of hearing disturbance, tinnitus, and a feeling of fullness in his right ear.
A, Axial CT image demonstrates bone destruction and soft tissue replacement of the anterior portion of the right temporal bone.
B, Axial T1-weighted MR image (416/9 [TR/TE]) shows a lesion (asterisk [*]) that is hypointense to the muscles in the right temporal area. The lesion occupies the anterior portion of the mastoid and extends to the middle cranial fossa.
C, Axial T2-weighted MR image (4000/126) shows that the lesion has mainly hypointense and several hyperintense foci in its central portion (arrow). The dark appearance of the lesion corresponds to areas of hemorrhage and hemosiderin deposition found at pathologic correlation.
D and E, Axial (D) and coronal (E) contrast-enhanced T1-weighted MR images (416/9) reveal mild heterogeneous enhancement of the lesion and show thickening and enhancement of the adjacent dura (E, arrows).
F, Photomicrograph shows that the tumor is composed mostly of clumps of reactive giant cells around abundant hemorrhagic foci mixed with osteoid formation.
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