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MR Findings in Murray Valley Encephalitis

Lloyd Einsiedela, Evelyn Katb, Janakan Ravindranc, John Slavotinekb and David L. Gordona

a Department of Microbiology and Infectious Diseases, Flinders Medical Centre, Adelaide, Australia
b Department of Medical Imaging, Flinders Medical Centre, Adelaide, Australia
c Department of Neurology, Flinders Medical Centre, Adelaide, Australia



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FIG 1. A, Axial spin-echo T1-weighted image (560/14 [TR/TE]) shows hypointensity of the thalami.

B, Axial fast spin-echo T2-weighted image (3641/80) showing hyperintensity of the thalami.

C, Coronal fast spin-echo T2-weighted image (3641/80) shows hyperintensity of both thalami, red nuclei, and substantia nigra.

D, Axial spin-echo T1-weighted image (570/14) reveals subtle heterogeneous enhancement within the thalami.

E and F, Single-shot spin-echo echo-planar axial diffusion-weighted image (E) with diffusion sensitivity of b = 1000 s/mm2 (4832/81) demonstrates bilateral thalamic high signal intensity. Corresponding apparent diffusion coefficient map (F) shows increased diffusion in the region of the thalami. This indicates that high signal intensity demonstrated on the diffusion-weighted images represents T2 shine-through rather than cytotoxic edema.

G, Sagittal fast spin-echo T2-weighted (2654/100) image of the cervical spine show diffuse hyperintensity of the central cord.

H, Axial gradient-echo T2-weighted (697/14; flip angle, 25°) image of cervical spine shows hyperintense gray matter within the cord.