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CT Characteristics of Intraocular Perfluoro-N-Octane

John B. Christoforidisa, Paul A. Carusob, Hugh D. Curtinb, Tito Fiorea and Donald J. D’Amicoa

a Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts
b Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts



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FIG 1. A, Axial CT scan without contrast demonstrates attenuated fluid collection within the posterior vitreous cavity (asterisk) and smaller deposits in the ora serrata region (arrowheads) forming a fluid-fluid level with the native vitreous humor. PFO can also be seen within the anterior chamber (white arrow).

B, Axial CT with bone algorithm and bone windows demonstrates a retinal detachment (black arrows) and the two components of the collection, the one anterior to the detached retina and the second within the subretinal space extending to the ora serrata. PFO is also seen within the anterior chamber (white arrows).

C, Coronal CT reformat with bone windows demonstrates the corrugated surface of the PFO collection corresponding to the PFO bubbles seen intraoperatively.



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FIG 2. A, External view of the eye showing multiple PFO bubbles over the inferior third of the anterior chamber.

B, Intraoperative view in the vitreous cavity showing the retracted opacified retina (upper left) and the extrusion canula removing multiple PFO bubbles from the subretinal space.



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FIG 3. A, Axial nonenhanced CT image of an enucleated porcine globe demonstrates the attenuated smoothly marginated globule of PFO deposited into the vitreous cavity.

B, T2-weighted MR image of an enucleated porcine globe demonstrates a hypointense oval collection lying dependently in the vitreous cavity.