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AJNR - American Journal of Neuroradiology

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Hemodynamic Changes after Occlusion of the Posterior Superior Sagittal Sinus: An Experimental PET Study in Cats

Bernhard Schaller^a, Rudolf Graf^a, Yasuhiro Sanada^a, Markus Tolnay^b, Gerhard Rosner^a, Klaus Wienhard^a and Wolf-Dieter Heiss^a

^a Max-Planck-Institute for Neurologic Research, Cologne, Germany
^b Department of Neuropathology, Institute of Pathology, University Hospitals, Basel, Switzerland

View larger version (54K): [in a new window]   FIG 1. Representative PET images and histologic sections. Top, Sequential PET images of CBF obtained at control and at 2 and 24 hours after SSS occlusion. Arrowheads indicate regions of main decreased flow. Middle, rCBF thresholds on PET images at >30 mL/100 g/min (red). Bottom, Representative cross-sections of subacute hemorrhagic infarct (HE stain). Low-power view (original magnification x100) shows subacute, focally extensive hemorrhagic necrosis accompanied by eosinophilic hypoxic-ischemic neuronal changes in the high-power view (original magnification x400).