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AJNR - American Journal of Neuroradiology

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Rapid Development of Optic Glioma in a Patient with Hybrid Phakomatosis: Neurofibromatosis Type 1 and Tuberous Sclerosis

Sami H. Erbay^a, Stephen A. Oljeski^a and Rafeeque Bhadelia^a

^a From the Department of Radiology, New England Medical Center and Tufts University School of Medicine, Boston, MA

View larger version (59K): [in a new window]   FIG 1. Coronal T1-weighted images (TR/TE: 523/14) with contrast enhancement and fat suppression and obtained through the orbits reveal an enhancing right-sided OG at age 8 months.

View larger version (59K): [in a new window]   FIG 2. Coronal T1-weighted images (TR/TE: 523/14) with contrast enhancement and fat suppression and obtained through the orbits demonstrate interval worsening of right-sided OG at age 18 months.

View larger version (59K): [in a new window]   FIG 3. Axial postcontrast T1-weighted images (TR/TE: 670/14) with fat saturation demonstrate marked worsening of right-sided proptosis due to rapid growth of the right OG at age 23 months).