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Neurobrucellosis: Clinical and Neuroimaging Correlation

M. Walid Al-Sousa, Saeed Bohlegaa, M. Zuheir Al-Kawia, Jehad Alwatbana and Donald R. McLeana

a Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia



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  		FIG 1. Patient 13.

A, Nonenhanced (top) and enhanced (bottom) brain CT scans show left small subthalamic hematoma with perivascular enhancement (left), left caudate lacunar infarct, and diffuse periventricular white matter hypoattenuation (right).

B, CT scans obtained 4 months after treatment show that hemorrhage and perivascular enhancement have disappeared, but lacunar infarcts and white matter abnormality persist.

C, Brain T2-weighted (top) and FLAIR (bottom) MR images show increased signal intensity in periventricular white matter



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  		FIG 2. Patient 6. Gadolinium-enhanced T1-weighted brain MR images obtained before (top) and after (bottom) treatment show disappearance of dural enhancement



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  		FIG 3. Patient 3.

A–C, Gadolinium-enhanced T1-weighted brain MR images show granuloma in the hypothalamus and pituitary granuloma.

D–F, Gadolinium-enhanced T1-weighted brain MR images obtained 4 months after treatment show resolution of the granuloma.



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  		FIG 4. Patient 9.

A–D, T1-weighted lumbar MR images obtained before (A and D) and after (B and C) injection of a gadolinium-based contrast agent show enhancement of the lumbar nerve root



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  		FIG 5. Patient 14. FLAIR brain MR images show diffuse peripheral subcortical white matter increased signal intensity with predilection to arcuate fibers.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X