MR Imaging Quantification of Cerebellar Growth Following Hypoxic-Ischemic Injury to the Neonatal Brain
Elisabeth Le Strangea,
Nadeem Saeeda,
Frances M. Cowanb,
A. David Edwardsb and
Mary A. Rutherforda,b
a Robert Steiner Magnetic Resonance Unit, Imaging Sciences Department
b Department of Pediatrics and Neonatal Medicine, Imperial College, Hammersmith Campus, London, England
View larger version (70K):
[in a new window]
|
FIG 1. T1-weighted MR images (860/20).
A, Day 5 image shows focal infarction. There is a loss of gray matter–white matter differentiation in the posterior lobe on the left. This is consistent with perinatal infarction within the territory of the left middle cerebral artery.
B, Day 12 image shows basal ganglia and thalamic lesions. There are persistent, abnormal high-signal-intensity regions in the posterior lentiform nuclei and lateral thalami (arrows). The intervening posterior limb of the internal capsule shows reduced high signal intensity from myelin.
| |
View larger version (11K):
[in a new window]
|
FIG 2. Total cerebellar volume versus age in all infants, by group (n = 20).
| |
View larger version (8K):
[in a new window]
|
FIG 3. Cerebellar hemispheres in infants with cerebral infarcts. Volume ipsilateral to the infarct versus volume contralateral to the infarct (n = 11). The line is the line of equality.
| |
View larger version (8K):
[in a new window]
|
FIG 4. Cerebellar hemispheres in all infants. Volume of the right hemisphere versus volume of the left hemisphere (n = 20). The line is the line of equality.
| |
View larger version (8K):
[in a new window]
|
FIG 5. Cross-sectional area of the vermis versus age (n = 20).
| |
View larger version (8K):
[in a new window]
|
FIG 6. Cross-sectional area of the vermis versus total cerebellar volume (n = 23).
| |
