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Amyloidosis Concurrently Involving the Sinonasal Cavities and Larynx

Shy-Chyi China, Girish Fatterpeckarc, Chuan-Hsiang Kaob, Cheng-Yu Chena and Peter M. Somc,d,e

a Department of Radiology, Tri-Service General, Hospital, Taipei, Taiwan
b Department of Otolaryngology—Head and Neck Surgery, Tri-Service General, Hospital, Taipei, Taiwan
c Department of Radiology, Mount Sinai School of Medicine, New York University, New York, New York
d Department of Otolaryngology, Mount Sinai School of Medicine, New York University, New York, New York
e Anatomy and Functional Morphology, Mount Sinai School of Medicine, New York University, New York, New York



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FIG 1. A, Coronal CT viewed at wide window settings shows fluffy calcifications (arrows) of the turbinates and sinus walls adjacent to a nasal mass. Soft tissue windowing shows entrapped secretions and inflammatory mucosal thickening in the right maxillary and sphenoid sinuses.

B, Axial T2-weighted MR image (TR/TE, 3000/96 ms) through the paranasal sinuses, demonstrates a predominantly hypointense lesion (arrows) involving the right sinonasal cavity. In contrast, entrapped secretions in the right maxillary and sphenoid sinuses have high T2-weighted signal intensity.

C, Contrast-enhanced, axial fat-suppressed T1-weighted image (TR/TE, 540/12 ms) demonstrates peripheral enhancement of the lesion (arrows).



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FIG 2. A, Coronal T1-weighted image through the larynx demonstrates a mass (arrows) involving the left false vocal cord with hypointensity similar to adjacent muscle. The lesion also has low signal intensity on T2-weighted images (not shown).

B, Contrast-enhanced axial T1-weighted, fat-suppressed image demonstrates a minimally enhanced submucosal lesion (arrow) surrounded by intense mucosal enhancement.